Intelligent single-particle analysis and sorting—being developed as an integrated path from sample handling to detection, real-time interpretation and selective action.
Event-linked processing and interpretation inform the intended sorting or manipulation step.
NanoSpec AI is Rhei BioTech’s flagship platform in development for intelligent single-particle analysis and sorting. It integrates microfluidic handling, optical detection, real-time signal processing, intelligent analysis and active sorting or manipulation within one developing instrument architecture.
Bulk measurements remain useful, but they can compress a heterogeneous population into one value. NanoSpec AI is being developed for questions that benefit from retaining individual-event information.
Retain a view of population spread instead of reporting only a central value.
Frame questions about low-abundance groups that may be less visible in pooled signals.
Connect analysis with a developing path toward selective sorting or manipulation.
NanoSpec AI is being developed to analyze individual particle events, process optical signals in real time, interpret heterogeneous populations and enable active sorting or manipulation. Intended application areas include lipid nanoparticles, extracellular vesicles, adeno-associated virus and biopharma R&D or CMC research.
Preserve particle-level information rather than reducing the complete population to one pooled value.
Connect optical event detection with immediate processing inside an integrated instrument workflow.
Support intelligent analysis of heterogeneity, distributions and relevant subpopulations.
Develop a path from analysis toward active sorting or manipulation of selected events.
At a high level, NanoSpec AI is designed to move individual events through a controlled microfluidic path, detect optical signals, process those signals in real time, apply intelligent analysis and trigger sorting or manipulation when appropriate. The complete workflow remains in development.
Structure the sample into a controlled event path.
Capture optical signals from individual events.
Connect detected signals to the processing architecture.
Process event information within the instrument workflow.
Interpret population structure and support decisions.
Link an interpreted event to a developing actuation path.
Event-linked processing and interpretation inform the intended sorting or manipulation step.
NanoSpec AI brings fluidics, optics, electronics, real-time processing, algorithms and physical actuation into a single developing platform architecture.
Signal acquisition and coordinated instrument control.
→02Structured sample handling and event delivery at small scales.
→03Individual-event signal capture as an integrated platform capability.
→04Timely processing designed to connect measurement with decisions.
→05Algorithmic interpretation of heterogeneous particle populations.
→06A developing route from detected events to selective physical action.
→These are intended application areas for a platform in development, not claims of validated application performance.
Particle-level investigation for LNP research workflows.
Explore applicationResolve heterogeneity in extracellular-vesicle research.
Explore applicationComplement bulk measurements in biopharma development workflows.
Explore applicationConcept illustrations / Research context, not application-validation evidence.
NanoSpec AI is not presented as commercially available. The platform architecture, application focus and development intent are public; validated specifications and application performance are not published until approved evidence is available.
Rhei BioTech will publish performance data, application evidence and technical resources when those materials are validated and approved for public release.
Public validation figures, methods and datasheets are not yet available. Contact Rhei BioTech for current approved platform information.
See the evidence framework