Scientific problem
The challenge: linking detection with trustworthy interpretation.
Detecting individual events is only one part of the workflow. Sample handling, signal quality, real-time processing and validation posture must work together before performance claims can be made.
Particle-level information
Why does a particle-level perspective matter?
AAV research questions can involve heterogeneous particle populations. Resolving individual events may provide an additional way to investigate distributions and subpopulations, subject to method validation and appropriate interpretation.